CRISPR

Precise in vivo functional analysis of DNA variants with base editing using ACEofBASEs target prediction
Single nucleotide variants (SNVs) are prevalent genetic factors shaping individual trait profiles and disease susceptibility. The …
PDF Code DOI ACEofBASEs
Precise in vivo functional analysis of DNA variants with base editing using ACEofBASEs target prediction
Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications
Genome editing with the CRISPR–Cas9 system has enabled unprecedented efficacy for reverse genetics and gene correction approaches. …
PDF DOI
Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications
CCTop: An Intuitive, Flexible and Reliable CRISPR/Cas9 Target Prediction Tool
Engineering of the CRISPR/Cas9 system has opened a plethora of new opportunities for site-directed mutagenesis and targeted genome …
PDF Code DOI CCTop
CCTop: An Intuitive, Flexible and Reliable CRISPR/Cas9 Target Prediction Tool